401

Psilocybin for major depression granted Breakthrough Therapy by FDA

344

Ask HN: Quitting Big Tech, what is it like?

287

Vinod Khosla Wins Ruling Threatening Public Beach Access

259

Google Fires Four Workers, Including Staffer Tied to Protest

254

I'm not burned out, I'm pissed off

224

Emacs: The Editor for the Next Forty Years [video]

220

Twitter prepares for cull of inactive users

213

Debuggers Suck

205

Big Calculator: How Texas Instruments Monopolized Math Class

164

Dark Mode by Default – 95% of People Prefer Dark over Light Mode

159

It's Way Too Easy to Get a .gov Domain Name

152

Show HN: Coscreen.co – a radically different remote collaboration tool

137

In mobile, 62.7% of energy is spent on data movement [pdf]

120

The LEGO Group acquires BrickLink

117

Fibery – yet another collaboration tool

115

It's 2019, but It Sure Feels a Lot Like 1998 for Stocks

113

Machine Learning on Encrypted Data Without Decrypting It

110

Firefox browser will block the IAB's DigiTrust universal ID

102

Can You Copyright Work Made by Artificial Intelligence?

97

HPE Drive fail at 32,768 hours without firmware update

97

Eternal Terminal

86

Atom editor still phones home prior to consent dialog

86

BorgBackup: Deduplicating Archiver

79

A Look at PureDarwin – An OS Based on the Open Source Core of macOS

78

Do we need a web API?

71

Pirate Act: what the law says and how it threatens pirate radio stations

70

The Zen of Weight Lifting

66

Excite CEO: Why Excite didn't buy Google (2014) [audio]

65

Health Concerns Mount as More Old Sewer Pipes Are Lined with Plastic

65

To Limit to 1.5C, Need to Cut Emissions by 7.6% per Year

61

Astrophotography with Night Sight on Pixel Phones

59

Show HN: patchbay.pub – Poor man's ngrok/IFTTT/serverless

54

Julia v1.3

52

Oil Is the New Data

52

Indiana manipulated report on Amazon worker’s death, investigation says

51

JSONCrush – Compress JSON into URI Friendly Strings

51

Apple’s Great GPL Purge (2012)

50

Instagram’s Explore Recommender System

50

Hours Worked by Women Age 55 to 61 Confound Labor Market Analysis

49

The heritability of self-control: A meta-analysis

48

Paradoxical Geniuses: “Let us burn the ships” (2017)

48

Building a language server for Muon

43

Thousand year-old windmills in Iran (2017)

43

Reverse Engineering for Beginners [pdf]

42

Senate Considers Banning Dial Phones (1930)

39

Calorie Counting × Meal Planning

39

Is It a ‘5’ or a ‘6’? The Answer Could Make an Art Fortune

38

Tesla Cybertruck vs. a Ford F-150: It's All About Friction

32

California school shooting shines light on murky 'ghost gun' world

31

Scala.js 1.0.0-RC1

31

AVX register corruption from signal delivery

31

Jor1k: Run Linux in the browser with multicore and network support

29

Latency/throughput tradeoffs, illustrated with coffee

28

Launch HN: Scanwell (YC S18) – At-home UTI test with same-day treatment options

27

Air pollution causes brain structure changes that resemble Alzheimer's disease

27

Ohio school districts sue Facebook for accepting ECOT ad purchases

25

Tendon stem cells enhance regeneration

24

Getting Started with APL (2017)

24

Show HN: Pgsh – branch Postgres like Git

23

Rescuers race to save 14,000 sheep on capsized cargo ship

20

Waymo says self-driving cars have been overhyped

20

Y Combinator Abruptly Shutters YC China

19

Our Startup Handbook

17

A scientific attempt to demystify meditation yielded astounding results

16

Understanding the generalization of ‘lottery tickets’ in neural networks

16

Applying machine learning and deep learning methods to audio analysis

15

Master–Slave Morality

15

Department of Homeland Security Recommends Passage of Drone Origin Security Act

14

Show HN: Gorse – A recommender system back end based on collaborative filtering

12

Smart Toaster Can’t Hold a Candle to the Apollo Computer

10

A Brief History of the Current Empirical Software Engineering Science Turf War

10

The Dawn of a New Command Line Interface (2017)

10

SinGAN: Learning a Generative Model from a Single Natural Image

10

China sets up Hong Kong crisis center in mainland

9

Nomogram

9

How Is Disinformation Gaming Ad Tech? [pdf]

6

The Vienna Bank Job

6

Permazen: Language-Natural Persistence Layer for Java

5

The Conquest of Ubiquity (1928)

5

Early Modern Drugs and Medicinal Cannibalism (2012)

4

How mantis shrimp make sense of the world

4

Another use for strace (isatty)

4

Mutation testing based on LLVM (2018) [pdf]

4

Bootstrap v4.4.0 Released

3

Welcoming Beat Games to Facebook

3

Observability Pipelines at Kubecon

3

Nabokov Was Right About Butterflies (2011)

2

Crash Blossoms (2010)

2

Don DeLillo's literary interpretation of an astronaut’s view of earth (2018)

2

The Meaning of Life Is Absurd

2

Dkeras: Distributed Keras Engine

2

John Gregory Bourke’s “Scatalogic Rites of All Nations” (2017)

1

Cluster management expressed in a high-level declarative language